Molecular techniques for respiratory diseases: MicroRNA and extracellular vesicles
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چکیده
منابع مشابه
Extracellular vesicles in parasitic diseases
Parasitic diseases affect billions of people and are considered a major public health issue. Close to 400 species are estimated to parasitize humans, of which around 90 are responsible for great clinical burden and mortality rates. Unfortunately, they are largely neglected as they are mainly endemic to poor regions. Of relevance to this review, there is accumulating evidence of the release of e...
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Cigarette smoking continues to be a major health hazard, and is involved in the mechanisms of developing various types of smoking-related diseases. Chronic obstructive pulmonary disease (COPD) is a representative disease mainly caused by cigarette smoke inhalation and is pathologically characterized by emphysema and fibrotic airway remodeling. In addition, the presence of COPD is associated wit...
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Background & Aims: Extracellular vesicles are double phospholipid layer vesicles releasing from several cells. These particles contain bio-molecules including mRNA, miRNA, DNA, proteins, and lipids which play a pivotal role in the cell to cell communication. Once delivered, they participate to change target cell function, fate, morphology, differentiation, and growth. The present study is a re...
متن کاملExtracellular Vesicle MicroRNA Transfer in Lung Diseases
MicroRNAs (miRNAs) are single-stranded, small non-coding RNAs that ate involved in the transcriptional and post-transcriptional regulation of gene expression. Recently, miRNAs were demonstrated to be effectively delivered to a target cell or tissue from a host cell via extracellular vesicles (EVs). These EVs can be detected in blood, urine, exhaled breath condensates, bronchoalveolar lavage flu...
متن کاملTechniques for the analysis of extracellular vesicles using flow cytometry.
Extracellular Vesicles (EVs) are small, membrane-derived vesicles found in bodily fluids that are highly involved in cell-cell communication and help regulate a diverse range of biological processes. Analysis of EVs using flow cytometry (FCM) has been notoriously difficult due to their small size and lack of discrete populations positive for markers of interest. Methods for EV analysis, while c...
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ژورنال
عنوان ژورنال: Respirology
سال: 2019
ISSN: 1323-7799,1440-1843
DOI: 10.1111/resp.13756